參與三磷酸核苷水解的酶是生化研究的主要重點(diǎn),目標(biāo)是了解和治療與癌癥、病毒感染、心血管和運(yùn)動(dòng)障礙等疾病有關(guān)的細(xì)胞過(guò)程。為了闡明這些酶的作用機(jī)制,通常需要將酶捕獲在它們的三磷酸結(jié)合狀態(tài)。
由于天然核苷酸的水解速率通常會(huì)阻礙這類(lèi)研究,因此常使用核苷酸類(lèi)似物,其水解速率要小得多,甚至完全耐水解。
Jena Bioscience 擁有超過(guò)20年的耐水解核苷酸制備經(jīng)驗(yàn),可為廣大客戶(hù)提供全面的產(chǎn)品組合:
α-磷酸修飾的核苷酸 | |
Adenosine Nucleotides | |
AMPαS - Solution | NU-1161 |
AMPαS – Solid | NU-1161 |
ATPαS | NU-408 |
dADPαS | NU-1165 |
dATPαS | NU-426 |
dAMPαS | NU-430 |
Guanosine Nucleotides | |
GMPαS | NU-1160 |
GTPαS | NU-409 |
dGDPαS | NU-1164 |
dGTPαS | NU-424 |
Uridine Nucleotides | |
UTPαS | NU-411 |
Cytidine Nucleotides | |
CTPαS | NU-436 |
dCMPαS | NU-447 |
dCTPαS | NU-425 |
Thymidine Nucleotides | |
dTTPαS | NU-410 |
α,β不可水解核苷酸 | |
Adenosine Nucleotides | |
ApCp | NU-420 |
ApCpp | NU-421 |
dApCpp | NU-432 |
ApNHp | NU-448 |
ApNHpp | NU-449 |
dApNHpp | NU-443 |
Guanosine Nucleotides | |
GpCp | NU-414 |
GpCpp | NU-405 |
dGpCpp | NU-431 |
dGpNHpp | NU-440 |
NPE-caged-GpCpp | NU-306 |
6-Thio-GpCp | NU-417 |
Uridine Nucleotides | |
dUpCp | NU-428 |
dUpNHp | NU-902 |
dUpCpp | NU-429 |
dUpNHpp | NU-903 |
UpNHpp | NU-930 |
Cytidine Nucleotides | |
CpCp | NU-441 |
CpCpp | NU-438 |
dCpCpp | NU-437 |
CpNHpp | NU-264 |
dCpNHpp | NU-439 |
Thymidine Nucleotides | |
dTpCpp | NU-895 |
dTpNHpp | NU-907 |
β-磷酸修飾的核苷酸 | |
Adenosine Nucleotides | |
ADPβS | NU-433 |
AppNH2 | NU-1126 |
Guanosine Nucleotides | |
GDPβS | NU-427 |
GppNH2 | NU-1136 |
Uridine Nucleotides | |
UDPβS | NU-442 |
β,γ不可水解核苷酸 | |
Adenosine Nucleotides | |
AppCp | NU-422 |
dAppCp | NU-259 |
AppNHp | NU-407 |
dAppNHp | NU-257 |
Mant-AppNHp | NU-214 |
NPE-caged-AppNHp | NU-305 |
EDA-AppNHp | NU-810 |
Etheno-AppNHp | NU-1104 |
8-Bromo-AppNHp | NU-116 |
8-Iodo-AppNHp | NU-115 |
2'-Bromo-dAppNHp | NU-104 |
2'-Iodo-dAppNHp | NU-103 |
Guanosine Nucleotides | |
GppCp | NU-402 |
dGppCp | NU-260 |
GppNHp | NU-401 |
GppNHp | NU-899 |
dGppNHp | NU-258 |
Mant-GppCp | NU-881 |
Mant-GppNHp | NU-207 |
Mant-dGppNHp | NU-208 |
6-Thio-GppCp | NU-418 |
6-Thio-GppNHp | NU-419 |
TNP-GppNHp | NU-218 |
Xanthosine Nucleotides | |
XppCp | NU-423 |
XppNHp | NU-996 |
Mant-XppNHp | NU-211 |
NPE-caged-XppNHp | NU-308 |
Inosine Nucleotides | |
IppNHp | NU-1204 |
Uridine Nucleotides | |
UppNHp – Solid | NU-415 |
UppCp | NU-255 |
dUppCp | NU-263 |
Cytosine Nucleotides | |
CppCp | NU-254 |
dCppCp | NU-261 |
Thymidine Nucleotides | |
dTppCp | NU-262 |
γ-磷酸修飾的核苷酸 | |
Adenosine Nucleotides | |
ATPγS | NU-406 |
dATPγS | NU-265 |
Mant-ATPγS | NU-232 |
2-Iodo-ATPγS | NU-905 |
N6-Benzyl-ATPγS | NU-241 |
Guanosine Nucleotides | |
GTPγS | NU-412 |
dGTPγS | NU-266 |
Mant-GTPγS | NU-209 |
Xanthosine Nucleotides | |
XTPγS | NU-404 |
Inosine Nucleotides | |
ITPγS | NU-413 |
Mant-ITPγS | NU-981 |
Uridine Nucleotides | |
UTPγS | NU-416 |
不可水解的二核苷酸 | |
ApCpp(Nic) | NU-515 |
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